This article is part of the Topical Collection onSystemic Lupus Erythematosus * Martin Aringer martin.aringer@uniklinikum-dresden.de Nicolai Leuchten The 2012 SLICC Classification Criteria for SLE Classify a patient as having SLE if a) The patient satisfies four of the criteria, including at least one … SLICC criteria is considered positive in two cases: 1. EULAR/ACR classification criteria for SLE. The SLICC criteria for SLE classification requires: 1) Fulfillment of at least four criteria, with at least one clinical criterion AND one immunologic criterion OR 2) Lupus nephritis as the sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. Consequently, the EULAR/ACR 2019 criteria have essentially come back to the NPSLE version of the ACR criteria . Ann Rheum Dis . Clinical Criteria Acute Cutaneous Lupus OR Subacute Cutaneous Lupus. Systemic Lupus Erythematosus (SLE) V1.1.2019 iv List of Tables Table 1. Lupus malar rash (malar discoid rash not counted), bullous lupus, toxic epidermal necrolysis variant of SLE, maculopapular lupus rash, photosensitive lupus rash (in the absence of … CONCLUSIONS:The EULAR/ACR 2019 criteria perform well among patients with early disease, men, women, white, black, Hispanic and Asian patients. SLICC 2012 criteria performed better than EULAR/ACR 2019 criteria. The new 2019 EULAR/ACR classification criteria for SLE requires a positive ANA as obligatory entry criterion. Aringer M, Costenbader K, Daikh D, et al. The 2019 EULAR/ACR SLE classification criteria project has resulted in new, validated classification criteria [1,2].With EULAR and ACR support throughout the project and a symmetrically built 12 head steering committee (), this has been a large transatlantic, and in several stages truly worldwide effort.We now think that it has reached its goals. Results: Weighted SLICC criteria and the EULAR/ACR 2019 criteria had less sensitivity but better specificity compared to the list-based revised ACR 1997 and SLICC 2012 classification criteria. Meeting: 2019 ACR/ARP Annual Meeting Keywords: classification criteria, Clinical practice, systemic lupus erythematosus (SLE) and slicc, undifferentiated connective … The SLICC 2012 criteria yielded the best sensitivity, while the ACR 1997 criteria had the best specificity. The demographic characteristics are detailed in Table 2. There were no statistically significant differences between any pair of rules with respect to overall agreement with the physician diagnosis. Other criteria were chosen from 7 clinical (constitutional, hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal) and 3 immunologic (antiphospholipid antibodies, complement proteins, SLE-specific antibodies) categories, and weighted from 2 to 10. Clinical criteria. The lupus criteria include a specific set of symptoms that your doctor can see, symptoms you report, your medical history, plus test results, to decide whether you have lupus. To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). The 1997 update of the 1982 ACR revised criteria for the classification of SLE..... 12 Table 2. Of the analysed patients, 23.4%, 17.4% and 14.7% met the ACR 1997, SLICC 2012 and EULAR/ACR 2019 classification criteria for SLE at baseline, respectively. ... 249 (85%) patients fulfilled the 2012 SLICC criteria and 261 (89%) patients fulfilled the 1997 ACR criteria. Lupus nephritis as sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. Dr. Michelle Petri has recieved the 2019 ACR Master Designation. The SLICC criteria added mononeuritis multiplex, myelitis and peripheral or cranial neuropathy , but all of these additional symptoms are uncommon and rarely important for classifying SLE. CONCLUSION: SLICC criteria were significantly more sensitive than ACR criteria in cSLE classification, especially early in the disease course. Neuropsychiatric manifestations of SLE were added in the 2012 SLICC classification criteria; disease definitions were refined to include delirium, psychosis, or seizure in the 2019 EULAR/ACR recommendations, and were evaluated for their sensitivity. The sensitivity of the SLICC … These criteria have superior sensitivity than the ACR criteria and/or superior specificity than the SLICC criteria across many subgroups. The median time from first disease manifestation to criteria fulfillment was shorter for the EULAR/ACR 2019 criteria (28.47 months) than the 1997 ACR criteria (45.3 months, p. 0.001) and similar to the SLICC 2012 criteria (33.2 months, p=0.89). ACR-97 criteria, with areas under the ROC curve of 0.801 and 0.780, respectively. The accuracy of the EULAR/ACR-2019 criteria for SLE classification was the highest (diagnostic odds ratio [DOR], 243.2), followed by the SLICC-2012 criteria (DOR, 157.3) and the ACR-1997 criteria (DOR, 78.8). International Collaborating Clinics (SLICC) criteria [7]and the new 2019 European League Against Rheumatism (EULAR)/ACR classification criteria [8†, 9†], discussing the rationale on the way. The sensitivity and specificity of the EULAR/ACR 2019, SLICC 2012 and ACR 1982/1997 criteria were evaluated. 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus. Clinical Criteria: 1. There was no significant difference in this proportion after follow-up. However, the mean SDI at last visit was lower among patients who never achieved the 2019 criteria, at 1.2 ± 1.7, compared with 2 ± 2.3 among those who did met the criteria (P = .0004). The sensitivity and specificity of the EULAR/ACR 2019, SLICC 2012 and ACR 1982/1997 criteria were evaluated. However, the 44 cases included by the ACR 97 criteria were served by the SLICC 12, that is, the SLICC 12 answered 14 more cases than the ACR 97 criteria. EVIDENCE BASED MEDICINE – SLICC criteria for SLE CMI 13:4 39 Oct 2015 Continued from page 38 Table 2. Mucocutaneous Criteria The classification performance of each criteria was analyzed alone and in combination with additional features. The honour is awarded to researchers who have made outstanding contributions to the ACR and the field of rheumatology through scholarly achievement and/or service to their patients, students, and profession. The sensitivity, specificity and accuracy of the different criteria are presented in table 2. 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